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Native Amides as Enabling Vehicles for Forging sp(3)–sp(3) Architectures via Interrupted Deaminative Ni-Catalyzed Chain-Walking

[Image: see text] Herein, we disclose an interrupted deaminative Ni-catalyzed chain-walking strategy that forges sp(3)–sp(3) architectures at remote, yet previously unfunctionalized, methylene sp(3) C–H sites enabled by the presence of native amides. This protocol is characterized by its mild condit...

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Detalles Bibliográficos
Autores principales: Rodrigalvarez, Jesus, Wang, Hao, Martin, Ruben
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2023
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10236437/
https://www.ncbi.nlm.nih.gov/pubmed/36753384
http://dx.doi.org/10.1021/jacs.2c12915