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Klotho enhances bone regenerative function of hPDLSCs via modulating immunoregulatory function and cell autophagy

BACKGROUND: Human periodontal ligament stem cells (hPDLSCs) have a superior ability to promote the formation of new bones and achieve tissue regeneration. However, mesenchymal stem cells (MSCs) are placed in harsh environments after transplantation, and the hostile microenvironment reduces their ste...

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Detalles Bibliográficos
Autores principales: Niu, Qingru, Chen, Huan, Ou, Qianmin, Yang, Shuqing, Peng, Yingying, Xie, Yunyi, Yu, Le, Cheng, Zhilan, Cao, Yang, Wang, Yan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10236596/
https://www.ncbi.nlm.nih.gov/pubmed/37264407
http://dx.doi.org/10.1186/s13018-023-03849-8