Frequent PIK3CA mutation in normal endometrial gland drives spheroid formation and may be involved in stem cell propagation

Recent studies reported the presence of oncogenic mutations in normal endometrial glands, but the biological significance remains unclear. The present study investigated the status of KRAS/PIK3CA driver mutations in normal endometrial glands as well as spheroids derived from single glands. The norma...

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Detalles Bibliográficos
Autores principales: Sato, Seiya, Nakayama, Kentaro, Kanno, Kosuke, Sultana, Razia, Ishikawa, Masako, Ishibashi, Tomoka, Yamashita, Hitomi, Kyo, Satoru
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10236626/
https://www.ncbi.nlm.nih.gov/pubmed/36843384
http://dx.doi.org/10.1111/cas.15767

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10236626/
https://www.ncbi.nlm.nih.gov/pubmed/36843384
http://dx.doi.org/10.1111/cas.15767

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