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Pleckstrin‐2‐promoted PPM1B degradation plays an important role in transforming growth factor‐β‐induced breast cancer cell invasion and metastasis

Transforming growth factor‐β (TGF‐β) is known to promote breast cancer cell migration, invasion, and dissemination; however, the underlying molecular mechanisms are not yet well characterized. Here, we report that TGF‐β induces pleckstrin‐2 (PLEK2) expression by Smad3 and signal transducer and activ...

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Detalles Bibliográficos
Autores principales: Du, Liping, Li, Junyan, Tian, Yonglu, Feng, Renqing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10236636/
https://www.ncbi.nlm.nih.gov/pubmed/36928924
http://dx.doi.org/10.1111/cas.15791