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Inhibition of protein kinase C delta leads to cellular senescence to induce anti‐tumor effects in colorectal cancer

Protein kinase C delta (PKCδ) is a multifunctional serine–threonine kinase implicated in cell proliferation, differentiation, tumorigenesis, and therapeutic resistance. However, the molecular mechanism of PKCδ in colorectal cancer (CRC) remains unclear. In this study, we showed that PKCδ acts as a n...

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Detalles Bibliográficos
Autores principales: Shimoyama, Yuya, Yamada, Kohji, Yoshida, Saishu, Kawamura, Akira, Hannya, Yoshito, Imaizumi, Yuta, Kumamoto, Tomotaka, Takeda, Yasuhiro, Shimoda, Masayuki, Eto, Ken, Yoshida, Kiyotsugu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10236638/
https://www.ncbi.nlm.nih.gov/pubmed/36851883
http://dx.doi.org/10.1111/cas.15768