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A liposomal carbohydrate vaccine, adjuvanted with an NKT cell agonist, induces rapid and enhanced immune responses and antibody class switching

BACKGROUND: Congenital disorders of glycosylation (CDGs) are genetic diseases caused by gene defects in glycan biosynthesis pathways, and there is an increasing number of patients diagnosed with CDGs. Because CDGs show many different clinical symptoms, their accurate clinical diagnosis is challengin...

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Detalles Bibliográficos
Autores principales: Jia, Ji-Xiang, Peng, Sen-Lin, Kalisa, Ndayambaje Yvan, Chao, Qiang, Zhou, Zhifang, Gao, Xiao-Dong, Wang, Ning
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10236646/
https://www.ncbi.nlm.nih.gov/pubmed/37264420
http://dx.doi.org/10.1186/s12951-023-01927-x