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HMGB1-induced activation of ER stress contributes to pulmonary artery hypertension in vitro and in vivo

BACKGROUND: HMGB1 and ER stress have been considered to participate in the progression of pulmonary artery hypertension (PAH). However, the molecular mechanism underlying HMGB1 and ER stress in PAH remains unclear. This study aims to explore whether HMGB1 induces pulmonary artery smooth muscle cells...

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Detalles Bibliográficos
Autores principales: Zhang, Qianqian, Chen, Yuqian, Wang, Qingting, Wang, Yan, Feng, Wei, Chai, Limin, Liu, Jin, Li, Danyang, Chen, Huan, Qiu, Yuanjie, Shen, Nirui, Shi, Xiangyu, Xie, Xinming, Li, Manxiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10236651/
https://www.ncbi.nlm.nih.gov/pubmed/37268944
http://dx.doi.org/10.1186/s12931-023-02454-x