Trigred motif 36 regulates neuroendocrine differentiation of prostate cancer via HK2 ubiquitination and GPx4 deficiency

Neuroendocrine prostate cancer (NEPC), the most lethal subtype of castration‐resistant prostate cancer (PCa), may evolve from the neuroendocrine differentiation (NED) of PCa cells. However, the molecular mechanism that triggers NED is unknown. Trigred motif 36 (TRIM36), a member of the TRIM protein...

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Detalles Bibliográficos
Autores principales: Zhao, Xusong, Zhou, Tianren, Wang, Yuhao, Bao, Meiling, Ni, Chenbo, Ding, Lei, Sun, Shengjie, Dong, Huiyu, Li, Jie, Liang, Chao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
ORIGINAL ARTICLES
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10236700/
https://www.ncbi.nlm.nih.gov/pubmed/36799474
http://dx.doi.org/10.1111/cas.15763

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10236700/
https://www.ncbi.nlm.nih.gov/pubmed/36799474
http://dx.doi.org/10.1111/cas.15763

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