Granzyme B + CD8 + T cells with terminal differentiated effector signature determine multiple sclerosis progression

BACKGROUND: Multiple sclerosis (MS) leads to demyelination and neurodegeneration with autoimmune responses in central nervous system. Patients begin with a relapsing–remitting (RR) course, and more than 80% of them may advance to secondary progressive MS (SPMS), which is characteristic for the gradu...

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Detalles Bibliográficos
Autores principales: Shi, Ziyan, Wang, Xiaofei, Wang, Jiancheng, Chen, Hongxi, Du, Qin, Lang, Yanlin, Kong, Lingyao, Luo, Wenqin, Qiu, Yuhan, Zhang, Ying, Li, Chen, Wen, Dingke, Yao, Jie, Cheng, Xia, Cai, Linjun, Lin, Xue, Wang, Rui, Mou, Zichao, Li, Shuangjie, Liu, Duanya, Zhou, Hong, Zhou, Hongyu, Yang, Mu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10236809/
https://www.ncbi.nlm.nih.gov/pubmed/37268957
http://dx.doi.org/10.1186/s12974-023-02810-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10236809/
https://www.ncbi.nlm.nih.gov/pubmed/37268957
http://dx.doi.org/10.1186/s12974-023-02810-0

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