A bifunctional bortezomib-loaded porous nano-hydroxyapatite/alginate scaffold for simultaneous tumor inhibition and bone regeneration

Treatments of osteolytic lesions due to malignant metastasis remain one of the major clinical challenges. The residual tumor cells after surgical resections and an acidic tumor microenvironment are unfavorable for osteogenic induction. Bortezomib (BTZ), a proteasome inhibitor used in chemotherapy, a...

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Detalles Bibliográficos
Autores principales: Chen, Jiafei, Wen, Junru, Fu, Yike, Li, Xiang, Huang, Jie, Guan, Xiaoxu, Zhou, Yi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10236870/
https://www.ncbi.nlm.nih.gov/pubmed/37264410
http://dx.doi.org/10.1186/s12951-023-01940-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10236870/
https://www.ncbi.nlm.nih.gov/pubmed/37264410
http://dx.doi.org/10.1186/s12951-023-01940-0

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