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Ubiquitin-independent proteasomal degradation driven by C-degron pathways

Although most eukaryotic proteins are targeted for proteasomal degradation by ubiquitination, a subset have been demonstrated to undergo ubiquitin-independent proteasomal degradation (UbInPD). However, little is known about the molecular mechanisms driving UbInPD and the degrons involved. Utilizing...

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Detalles Bibliográficos
Autores principales: Makaros, Yaara, Raiff, Anat, Timms, Richard T., Wagh, Ajay R., Gueta, Mor Israel, Bekturova, Aizat, Guez-Haddad, Julia, Brodsky, Sagie, Opatowsky, Yarden, Glickman, Michael H., Elledge, Stephen J., Koren, Itay
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10237035/
https://www.ncbi.nlm.nih.gov/pubmed/37201526
http://dx.doi.org/10.1016/j.molcel.2023.04.023