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Wingless/It/β-catenin signaling in liver metastasis from colorectal cancer: A focus on biological mechanisms and therapeutic opportunities

The liver is the most common site of metastases in patients with colorectal cancer. Colorectal liver metastases (CRLMs) are the result of molecular mechanisms that involve different cells of the liver microenvironment. The aberrant activation of Wingless/It (Wnt)/β-catenin signals downstream of Wnt...

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Detalles Bibliográficos
Autores principales: Selvaggi, Federico, Catalano, Teresa, Lattanzio, Rossano, Cotellese, Roberto, Aceto, Gitana Maria
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Baishideng Publishing Group Inc 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10237106/
https://www.ncbi.nlm.nih.gov/pubmed/37274070
http://dx.doi.org/10.3748/wjg.v29.i18.2764