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Andrographolide alleviates paraquat-induced acute lung injury by activating the Nrf2/HO-1 pathway

OBJECTIVE(S): Paraquat (PQ), a highly effective and rapidly non-selective herbicide, mainly targets the lungs and causes acute lung injury (ALI). So far, the scarcity of effective drug candidates against PQ-induced ALI remains a big challenge. Andrographolide (Andro), with its anti-inflammatory and...

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Detalles Bibliográficos
Autores principales: Zhang, Degang, Shen, Fengqin, Ma, Shiting, Nan, Suting, Ma, Yanhong, Ren, Lili, Li, Hao, Yu, Qin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Mashhad University of Medical Sciences 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10237162/
https://www.ncbi.nlm.nih.gov/pubmed/37275765
http://dx.doi.org/10.22038/IJBMS.2023.68827.15000