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TrkA inhibition alleviates bladder overactivity in cyclophosphamide-induced cystitis by targeting hyperpolarization-activated cyclic nucleotide-gated channels

OBJECTIVE(S): To investigate the potential of Tropomyosin receptor kinase A (TrkA) for the treatment of interstitial cystitis/ bladder pain syndrome (IC/BPS). MATERIALS AND METHODS: Sixty-four female rats were randomly assigned to the control and cyclophosphamide (CYP) groups. Quantitative reverse t...

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Detalles Bibliográficos
Autores principales: Liu, Qian, Li, Xiaodong, Zhu, Jingzhen, Sun, Bishao, Li, Shadan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Mashhad University of Medical Sciences 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10237166/
https://www.ncbi.nlm.nih.gov/pubmed/37275761
http://dx.doi.org/10.22038/IJBMS.2023.68528.14943