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Irisin attenuates angiotensin II-induced atrial fibrillation and atrial fibrosis via LOXL2 and TGFβ1/Smad2/3 signaling pathways

OBJECTIVE(S): Irisin was reported as a cardioprotective and anti-oxidative effector, while the effect on atrial fibrosis is unknown. The current research examined irisin’s function in atrial fibrillation (AF); atrial fibrosis brought on by Ang II can be suppressed, thus lessening the risk of develop...

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Detalles Bibliográficos
Autores principales: Wu, Yingbiao, Luo, Jun, Song, Xiang, Gu, Wei, Wang, Saihua, Hao, Shuwen, Dong, Zhiwu, Ning, Zhongping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Mashhad University of Medical Sciences 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10237168/
https://www.ncbi.nlm.nih.gov/pubmed/37275755
http://dx.doi.org/10.22038/IJBMS.2023.68639.14967