Gigaxonin is required for intermediate filament transport

Gigaxonin is an adaptor protein for E3 ubiquitin ligase substrates. It is necessary for ubiquitination and degradation of intermediate filament (IF) proteins. Giant axonal neuropathy is a pathological condition caused by mutations in the GAN gene that encodes gigaxonin. This condition is characteriz...

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Detalles Bibliográficos
Autores principales: Renganathan, Bhuvanasundar, Zewe, James P., Cheng, Yuan, Paumier, Jean‐Michel, Kittisopikul, Mark, Ridge, Karen M., Opal, Puneet, Gelfand, Vladimir I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10237250/
https://www.ncbi.nlm.nih.gov/pubmed/37043392
http://dx.doi.org/10.1096/fj.202202119R

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10237250/
https://www.ncbi.nlm.nih.gov/pubmed/37043392
http://dx.doi.org/10.1096/fj.202202119R

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