Cargando…

Gigaxonin is required for intermediate filament transport

Gigaxonin is an adaptor protein for E3 ubiquitin ligase substrates. It is necessary for ubiquitination and degradation of intermediate filament (IF) proteins. Giant axonal neuropathy is a pathological condition caused by mutations in the GAN gene that encodes gigaxonin. This condition is characteriz...

Descripción completa

Detalles Bibliográficos
Autores principales:	Renganathan, Bhuvanasundar, Zewe, James P., Cheng, Yuan, Paumier, Jean‐Michel, Kittisopikul, Mark, Ridge, Karen M., Opal, Puneet, Gelfand, Vladimir I.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2023
Materias:	Research Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10237250/ https://www.ncbi.nlm.nih.gov/pubmed/37043392 http://dx.doi.org/10.1096/fj.202202119R

Ejemplares similares

The role of gigaxonin in the degradation of the glial-specific intermediate filament protein GFAP
por: Lin, Ni-Hsuan, et al.
Publicado: (2016)

Kelch Domain of Gigaxonin Interacts with Intermediate Filament Proteins Affected in Giant Axonal Neuropathy
por: Johnson-Kerner, Bethany L., et al.
Publicado: (2015)

Axonal Transport Defect in Gigaxonin Deficiency Rescued by Tubastatin A
por: Nath, Banshi, et al.
Publicado: (2023)

Explaining intermediate filament accumulation in giant axonal neuropathy
por: Opal, Puneet, et al.
Publicado: (2013)

Abnormal intermediate filament organization alters mitochondrial motility in giant axonal neuropathy fibroblasts
por: Lowery, Jason, et al.
Publicado: (2016)

Microtubule-dependent transport and dynamics of vimentin intermediate filaments
por: Hookway, Caroline, et al.
Publicado: (2015)

Sensory-motor deficits and neurofilament disorganization in gigaxonin-null mice
por: Ganay, Thibault, et al.
Publicado: (2011)

HILI destabilizes microtubules by suppressing phosphorylation and Gigaxonin-mediated degradation of TBCB
por: Tan, Hao, et al.
Publicado: (2017)

E3 Ubiquitin Ligases in Neurological Diseases: Focus on Gigaxonin and Autophagy
por: Lescouzères, Léa, et al.
Publicado: (2020)

Vimentin intermediate filaments modulate the motility of mitochondria
por: Nekrasova, Oxana E., et al.
Publicado: (2011)

Microtubule-associated protein 1B: a neuronal binding partner for gigaxonin
por: Ding, Jianqing, et al.
Publicado: (2002)

Intermediate filaments
por: Steinert, P. M., et al.
Publicado: (1984)

Gigaxonin E3 ligase governs ATG16L1 turnover to control autophagosome production
por: Scrivo, Aurora, et al.
Publicado: (2019)

Intermediate filament dysregulation and astrocytopathy in the human disease model of KLHL16 mutation in giant axonal neuropathy (GAN)
por: Battaglia, Rachel, et al.
Publicado: (2023)

Deimination, Intermediate Filaments and Associated Proteins
por: Briot, Julie, et al.
Publicado: (2020)

APC binds intermediate filaments and is required for their reorganization during cell migration
por: Sakamoto, Yasuhisa, et al.
Publicado: (2013)

Intermediate Filaments on the Move
por: Chou, Ying-Hao, et al.
Publicado: (2000)

Giant axonal neuropathy: The first Iranian case with a variation in the gigaxonin gene and a glance to the other cases
por: Vafaee-Shahi, Mohammad, et al.
Publicado: (2020)

A requirement for cytoplasmic dynein and dynactin in intermediate filament network assembly and organization
por: Helfand, Brian T., et al.
Publicado: (2002)

Endoplasmic spreading requires coalescence of vimentin intermediate filaments at force-bearing adhesions
por: Lynch, Christopher D., et al.
Publicado: (2013)

Epithelial cell migration requires the interaction between the vimentin and keratin intermediate filaments
por: Velez-delValle, Cristina, et al.
Publicado: (2016)

A molecular model of human Lysyl Oxidase (LOX) with optimal copper orientation in the catalytic cavity for induced fit docking studies with potential modulators
por: Bhuvanasundar, Renganathan, et al.
Publicado: (2014)

Dynamics of the neuronal intermediate filaments
Publicado: (1993)

Intermediate filaments in nervous tissues
por: Liem, RKH, et al.
Publicado: (1978)

Plasticity of Intermediate Filament Subunits
por: Kirmse, Robert, et al.
Publicado: (2010)

The Diversity of Intermediate Filaments in Astrocytes
por: Potokar, Maja, et al.
Publicado: (2020)

Capturing intermediate filament networks
por: Coulombe, Pierre A
Publicado: (2022)

Influence of phosphorylation on intermediate filaments
por: Kraxner, Julia, et al.
Publicado: (2023)

Purification of the 300K intermediate filament-associated protein and its in vitro recombination with intermediate filaments
Publicado: (1985)

The instability of the BTB-KELCH protein Gigaxonin causes Giant Axonal Neuropathy and constitutes a new penetrant and specific diagnostic test
por: Boizot, Alexia, et al.
Publicado: (2014)

Molecular evolution of type VI intermediate filament proteins
por: Guérette, Dominique, et al.
Publicado: (2007)

Assembly of type IV neuronal intermediate filaments in nonneuronal cells in the absence of preexisting cytoplasmic intermediate filaments
Publicado: (1993)

Dynactin is required for bidirectional organelle transport
por: Deacon, Sean W., et al.
Publicado: (2003)

Intermediate filaments and the initiation of desmosome assembly
Publicado: (1985)

Dual regulation of intermediate filament phosphorylation
Publicado: (1984)

Correction: Plasticity of Intermediate Filament Subunits
por: Kirmse, Robert, et al.
Publicado: (2010)

Role of Intermediate Filaments in Vesicular Traffic
por: Margiotta, Azzurra, et al.
Publicado: (2016)

Intermediate Filaments and Polarization in the Intestinal Epithelium
por: Coch, Richard A., et al.
Publicado: (2016)

Paraneoplastic neuronal intermediate filament autoimmunity
por: Basal, Eati, et al.
Publicado: (2018)

Model for Bundling of Keratin Intermediate Filaments
por: Haimov, Ehud, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_lq3nobir3veij3n1irjpeugeve