TMPRSS2 Inhibitor Discovery Facilitated through an In Silico and Biochemical Screening Platform

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[Image: see text] The COVID-19 pandemic has highlighted the need for new antiviral approaches because many of the currently approved drugs have proven ineffective against mitigating SARS-CoV-2 infections. The host transmembrane serine protease TMPRSS2 is a promising antiviral target because it plays...

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Detalles Bibliográficos
Autores principales: Peiffer, Amanda L., Garlick, Julie M., Wu, Yujin, Wotring, Jesse W., Arora, Sahil, Harmata, Alexander S., Bochar, Daniel A., Stephenson, Corey J., Soellner, Matthew B., Sexton, Jonathan Z., Brooks, Charles L., Mapp, Anna K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2023
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10237299/
https://www.ncbi.nlm.nih.gov/pubmed/37284689
http://dx.doi.org/10.1021/acsmedchemlett.3c00035

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10237299/
https://www.ncbi.nlm.nih.gov/pubmed/37284689
http://dx.doi.org/10.1021/acsmedchemlett.3c00035

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