Plasma Progerin in Patients With Hutchinson-Gilford Progeria Syndrome: Immunoassay Development and Clinical Evaluation

Hutchinson-Gilford progeria syndrome (HGPS) is an ultrarare, fatal, premature aging disease caused by a toxic protein called progerin. Circulating progerin has not been previously detected, precluding research using readily available biological samples. This study aimed to develop a plasma progerin...

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Detalles Bibliográficos
Autores principales: Gordon, Leslie B., Norris, Wendy, Hamren, Sarah, Goodson, Robert, LeClair, Jessica, Massaro, Joseph, Lyass, Asya, D’Agostino, Ralph B., Tuminelli, Kelsey, Kieran, Mark W., Kleinman, Monica E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2023
Materias:
Original Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10237348/
https://www.ncbi.nlm.nih.gov/pubmed/36919608
http://dx.doi.org/10.1161/CIRCULATIONAHA.122.060002

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10237348/
https://www.ncbi.nlm.nih.gov/pubmed/36919608
http://dx.doi.org/10.1161/CIRCULATIONAHA.122.060002

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