Elastin-targeted nanoparticles delivering doxycycline mitigate cytokine storm and reduce immune cell infiltration in LPS-mediated lung inflammation

BACKGROUND AND PURPOSE: Cytokine storm invoked during acute and chronic lung injury promotes alveolar damage and remodeling. The current study shows that degraded elastin-targeted nanoparticles releasing doxycycline (Doxy NPs) are potent in mitigating cytokines storm, migration of immune cells in th...

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Detalles Bibliográficos
Autores principales: Arora, Shivani, Vyavahare, Narendra
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10237374/
https://www.ncbi.nlm.nih.gov/pubmed/37267267
http://dx.doi.org/10.1371/journal.pone.0286211

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10237374/
https://www.ncbi.nlm.nih.gov/pubmed/37267267
http://dx.doi.org/10.1371/journal.pone.0286211

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