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Phase I study of a novel glioblastoma radiation therapy schedule exploiting cell-state plasticity
BACKGROUND: Glioblastomas comprise heterogeneous cell populations with dynamic, bidirectional plasticity between treatment-resistant stem-like and treatment-sensitive differentiated states, with treatment influencing this process. However, current treatment protocols do not account for this plastici...
Autores principales: | , , , , , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10237407/ https://www.ncbi.nlm.nih.gov/pubmed/36402744 http://dx.doi.org/10.1093/neuonc/noac253 |