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Phase I study of a novel glioblastoma radiation therapy schedule exploiting cell-state plasticity

BACKGROUND: Glioblastomas comprise heterogeneous cell populations with dynamic, bidirectional plasticity between treatment-resistant stem-like and treatment-sensitive differentiated states, with treatment influencing this process. However, current treatment protocols do not account for this plastici...

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Detalles Bibliográficos
Autores principales:	Dean, Jamie A, Tanguturi, Shyam K, Cagney, Daniel, Shin, Kee-Young, Youssef, Gilbert, Aizer, Ayal, Rahman, Rifaquat, Hammoudeh, Lubna, Reardon, David, Lee, Eudocia, Dietrich, Jorg, Tamura, Kaoru, Aoyagi, Masaru, Wickersham, Lacey, Wen, Patrick Y, Catalano, Paul, Haas-Kogan, Daphne, Alexander, Brian M, Michor, Franziska
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2022
Materias:	Clinical Investigations
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10237407/ https://www.ncbi.nlm.nih.gov/pubmed/36402744 http://dx.doi.org/10.1093/neuonc/noac253

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