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Incidence and determinants of hematotoxicity in acute lymphoblastic leukemia children who received 6-mercaptopurine based maintenance therapy in Addis Ababa, Ethiopia

INTRODUCTION: The maintenance phase of acute lymphoblastic leukemia treatment is the final and longest stage of treatment, mainly focused on antimetabolite therapy. This phase is essential to eliminate residual leukemic clones and prevent relapse. However, dose-limiting hematotoxicity is a major pro...

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Detalles Bibliográficos
Autores principales: Ali, Awol Mekonnen, Adam, Haileyesus, Hailu, Daniel, Coenen, Marieke J. H., Howe, Rawleigh, Abula, Teferra
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10237636/
https://www.ncbi.nlm.nih.gov/pubmed/37267380
http://dx.doi.org/10.1371/journal.pone.0286544