Cargando…

Pbp1 associates with Puf3 and promotes translation of its target mRNAs involved in mitochondrial biogenesis

Pbp1 (poly(A)-binding protein—binding protein 1) is a cytoplasmic stress granule marker that is capable of forming condensates that function in the negative regulation of TORC1 signaling under respiratory conditions. Polyglutamine expansions in its mammalian ortholog ataxin-2 lead to spinocerebellar...

Descripción completa

Detalles Bibliográficos
Autores principales: van de Poll, Floortje, Sutter, Benjamin M., Acoba, Michelle Grace, Caballero, Daniel, Jahangiri, Samira, Yang, Yu-San, Lee, Chien-Der, Tu, Benjamin P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10237644/
https://www.ncbi.nlm.nih.gov/pubmed/37216416
http://dx.doi.org/10.1371/journal.pgen.1010774