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Pbp1 associates with Puf3 and promotes translation of its target mRNAs involved in mitochondrial biogenesis
Pbp1 (poly(A)-binding protein—binding protein 1) is a cytoplasmic stress granule marker that is capable of forming condensates that function in the negative regulation of TORC1 signaling under respiratory conditions. Polyglutamine expansions in its mammalian ortholog ataxin-2 lead to spinocerebellar...
| Autores principales: | , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10237644/ https://www.ncbi.nlm.nih.gov/pubmed/37216416 http://dx.doi.org/10.1371/journal.pgen.1010774 |