Design and synthesis of novel anti-urease imidazothiazole derivatives with promising antibacterial activity against Helicobacter pylori

Urease enzyme is a known therapeutic drug target for treatment of Helicobacter pylori infection due to its role in settlement and growth in gastric mucosa. In this study, we designed a new series of sulfonates and sulfamates bearing imidazo[2,1-b]thiazole scaffold that exhibit a potent inhibitory ac...

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Detalles Bibliográficos
Autores principales: Shahin, Afnan I., Zaib, Sumera, Zaraei, Seyed-Omar, Kedia, Reena A., Anbar, Hanan S., Younas, Muhammad Tayyab, Al-Tel, Taleb H., Khoder, Ghalia, El-Gamal, Mohammed I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10237672/
https://www.ncbi.nlm.nih.gov/pubmed/37267378
http://dx.doi.org/10.1371/journal.pone.0286684

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10237672/
https://www.ncbi.nlm.nih.gov/pubmed/37267378
http://dx.doi.org/10.1371/journal.pone.0286684

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