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Cohesin-independent STAG proteins interact with RNA and R-loops and promote complex loading

Most studies of cohesin function consider the Stromalin Antigen (STAG/SA) proteins as core complex members given their ubiquitous interaction with the cohesin ring. Here, we provide functional data to support the notion that the SA subunit is not a mere passenger in this structure, but instead plays...

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Detalles Bibliográficos
Autores principales: Porter, Hayley, Li, Yang, Neguembor, Maria Victoria, Beltran, Manuel, Varsally, Wazeer, Martin, Laura, Cornejo, Manuel Tavares, Pezić, Dubravka, Bhamra, Amandeep, Surinova, Silvia, Jenner, Richard G, Cosma, Maria Pia, Hadjur, Suzana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10238091/
https://www.ncbi.nlm.nih.gov/pubmed/37010886
http://dx.doi.org/10.7554/eLife.79386