Myoglobin-derived iron causes wound enlargement and impaired regeneration in pressure injuries of muscle

The reasons for poor healing of pressure injuries are poorly understood. Vascular ulcers are worsened by extracellular release of hemoglobin, so we examined the impact of myoglobin (Mb) iron in murine muscle pressure injuries (mPI). Tests used Mb-knockout or treatment with deferoxamine iron chelator...

Descripción completa

Detalles Bibliográficos
Autores principales: Nasir, Nurul Jannah Mohamed, Heemskerk, Hans, Jenkins, Julia, Hamadee, Nur Hidayah, Bunte, Ralph, Tucker-Kellogg, Lisa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2023
Materias:
Stem Cells and Regenerative Medicine
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10238093/
https://www.ncbi.nlm.nih.gov/pubmed/37267120
http://dx.doi.org/10.7554/eLife.85633

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10238093/
https://www.ncbi.nlm.nih.gov/pubmed/37267120
http://dx.doi.org/10.7554/eLife.85633

Ejemplares similares