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The RNA Interference Effector Protein Argonaute 2 Functions as a Restriction Factor Against SARS-CoV-2
Argonaute 2 (Ago2) is a key component of the RNA interference (RNAi) pathway, a gene-regulatory system that is present in most eukaryotes. Ago2 uses microRNAs (miRNAs) and small interfering RNAs (siRNAs) for targeting to homologous mRNAs which are then degraded or translationally suppressed. In plan...
Autores principales: | , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Published by Elsevier Ltd.
2023
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10238125/ https://www.ncbi.nlm.nih.gov/pubmed/37271493 http://dx.doi.org/10.1016/j.jmb.2023.168170 |