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The RNA Interference Effector Protein Argonaute 2 Functions as a Restriction Factor Against SARS-CoV-2

Argonaute 2 (Ago2) is a key component of the RNA interference (RNAi) pathway, a gene-regulatory system that is present in most eukaryotes. Ago2 uses microRNAs (miRNAs) and small interfering RNAs (siRNAs) for targeting to homologous mRNAs which are then degraded or translationally suppressed. In plan...

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Detalles Bibliográficos
Autores principales: Lopez-Orozco, Joaquin, Fayad, Nawell, Khan, Juveriya Qamar, Felix-Lopez, Alberto, Elaish, Mohamed, Rohamare, Megha, Sharma, Maansi, Falzarano, Darryl, Pelletier, Jerry, Wilson, Joyce, Hobman, Tom C., Kumar, Anil
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Published by Elsevier Ltd. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10238125/
https://www.ncbi.nlm.nih.gov/pubmed/37271493
http://dx.doi.org/10.1016/j.jmb.2023.168170