Glutathione‐Scavenging Nanoparticle‐Mediated PROTACs Delivery for Targeted Protein Degradation and Amplified Antitumor Effects

PROteolysis TArgeting Chimeras (PROTACs) are an emerging class of promising therapeutic modalities that selectively degrade intracellular proteins of interest by hijacking the ubiquitin‐proteasome system. However, the lack of techniques to efficiently transport these degraders to targeted cells and...

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Detalles Bibliográficos
Autores principales: Liu, Hai‐Jun, Chen, Wei, Wu, Gongwei, Zhou, Jun, Liu, Chuang, Tang, Zhongmin, Huang, Xiangang, Gao, Jingjing, Xiao, Yufen, Kong, Na, Joshi, Nitin, Cao, Yihai, Abdi, Reza, Tao, Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10238184/
https://www.ncbi.nlm.nih.gov/pubmed/37066758
http://dx.doi.org/10.1002/advs.202207439

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10238184/
https://www.ncbi.nlm.nih.gov/pubmed/37066758
http://dx.doi.org/10.1002/advs.202207439

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