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Silencing of NOTCH3 Signaling in Meniscus Smooth Muscle Cells Inhibits Fibrosis and Exacerbates Degeneration in a HEYL‐Dependent Manner

The mechanisms of meniscus fibrosis and novel ways to enhance fibrosis is unclear. This work reveals human meniscus fibrosis initiated at E24 weeks. Smooth muscle cell cluster is identified in embryonic meniscus, and the combined analysis with previous data suggests smooth muscle cell in embryonic m...

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Detalles Bibliográficos
Autores principales: Sun, Hao, Liu, Fangzhou, Lin, Zhencan, Jiang, Zongrui, Wen, Xingzhao, Xu, Jie, Zhang, Zhiqi, Ma, Ruofan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10238196/
https://www.ncbi.nlm.nih.gov/pubmed/37026620
http://dx.doi.org/10.1002/advs.202207020