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Exosomal circSPIRE1 mediates glycosylation of E-cadherin to suppress metastasis of renal cell carcinoma

Metastasis is the main cause of mortality in renal cell carcinoma (RCC). Circular RNAs (circRNAs) involvement in RCC metastasis has been described, although the underlying mechanisms remain unknown. We evaluated recurring lung-metastasis cases using patient-derived xenograft models and isolated a hi...

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Detalles Bibliográficos
Autores principales: Shu, Guannan, Lu, Xuanxuan, Pan, Yihui, Cen, Junjie, Huang, Kangbo, Zhou, Mi, Lu, Jun, Dong, Jiaqi, Han, Hui, Chen, Wei, Lin, Juan, Luo, Junhang, Zhang, Jiaxing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10238271/
https://www.ncbi.nlm.nih.gov/pubmed/37046045
http://dx.doi.org/10.1038/s41388-023-02678-7