Cargando…

Exosomal circSPIRE1 mediates glycosylation of E-cadherin to suppress metastasis of renal cell carcinoma

Metastasis is the main cause of mortality in renal cell carcinoma (RCC). Circular RNAs (circRNAs) involvement in RCC metastasis has been described, although the underlying mechanisms remain unknown. We evaluated recurring lung-metastasis cases using patient-derived xenograft models and isolated a hi...

Descripción completa

Detalles Bibliográficos
Autores principales:	Shu, Guannan, Lu, Xuanxuan, Pan, Yihui, Cen, Junjie, Huang, Kangbo, Zhou, Mi, Lu, Jun, Dong, Jiaqi, Han, Hui, Chen, Wei, Lin, Juan, Luo, Junhang, Zhang, Jiaxing
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10238271/ https://www.ncbi.nlm.nih.gov/pubmed/37046045 http://dx.doi.org/10.1038/s41388-023-02678-7

Ejemplares similares

CircNTNG1 inhibits renal cell carcinoma progression via HOXA5-mediated epigenetic silencing of Slug
por: Liang, Yanping, et al.
Publicado: (2022)

Correction: CircNTNG1 inhibits renal cell carcinoma progression via HOXA5-mediated epigenetic silencing of Slug
por: Liang, Yanping, et al.
Publicado: (2023)

Chitosan‐Gelatin‐EGCG Nanoparticle‐Meditated LncRNA TMEM44‐AS1 Silencing to Activate the P53 Signaling Pathway for the Synergistic Reversal of 5‐FU Resistance in Gastric Cancer
por: Zhou, Mi, et al.
Publicado: (2022)

Extracellular Vesicle-Mediated Transfer of LncRNA IGFL2-AS1 Confers Sunitinib Resistance in Renal Cell Carcinoma
por: Pan, Yihui, et al.
Publicado: (2023)

Circular RNA circSDHC serves as a sponge for miR-127-3p to promote the proliferation and metastasis of renal cell carcinoma via the CDKN3/E2F1 axis
por: Cen, Junjie, et al.
Publicado: (2021)

EGCG‐LYS Fibrils‐Mediated CircMAP2K2 Silencing Decreases the Proliferation and Metastasis Ability of Gastric Cancer Cells in Vitro and in Vivo
por: Dong, Jiaqi, et al.
Publicado: (2023)

Dr. Clayton E. Spire
Publicado: (1917)

Regulatory interactions between two actin nucleators, Spire and Cappuccino
por: Quinlan, Margot E., et al.
Publicado: (2007)

EHBP1L1 Drives Immune Evasion in Renal Cell Carcinoma through Binding and Stabilizing JAK1
por: Pan, Yihui, et al.
Publicado: (2023)

Exosomal circRNAs: Emerging Players in Tumor Metastasis
por: Zhou, Hao, et al.
Publicado: (2021)

Spliced integrated retrotransposed element (SpIRE) formation in the human genome
por: Larson, Peter A., et al.
Publicado: (2018)

Actin nucleator Spire 1 is a regulator of ectoplasmic specialization in the testis
por: Wen, Qing, et al.
Publicado: (2018)

Spire stimulates nucleation by Cappuccino and binds both ends of actin filaments
por: Bradley, Alexander O., et al.
Publicado: (2020)

Effect of PCSK9 Inhibition on the Plasma Proteome: A SPIRE SubStudy
por: Kraaijenhof, Jordan M., et al.
Publicado: (2023)

Hsa_circ_0057105 modulates a balance of epithelial‐mesenchymal transition and ferroptosis vulnerability in renal cell carcinoma
por: Cen, Junjie, et al.
Publicado: (2023)

The putative tumor suppressor microRNA-30a-5p modulates clear cell renal cell carcinoma aggressiveness through repression of ZEB2
por: Chen, Zhenhua, et al.
Publicado: (2017)

Services for High Energy Physics EGI-InSPIRE EU deliverable: MS603
por: Sciaba, A, et al.
Publicado: (2010)

Spire-Type Actin Nucleators Cooperate with Formin-2 to Drive Asymmetric Oocyte Division
por: Pfender, Sybille, et al.
Publicado: (2011)

Spire, an Actin Nucleation Factor, Regulates Cell Division during Drosophila Heart Development
por: Xu, Peng, et al.
Publicado: (2012)

A mitochondria-anchored isoform of the actin-nucleating spire protein regulates mitochondrial division
por: Manor, Uri, et al.
Publicado: (2015)

SPIRE—a software tool for bicontinuous phase recognition: application for plastid cubic membranes
por: Hain, Tobias M, et al.
Publicado: (2021)

Exosomal PD-L1 and N-cadherin predict pulmonary metastasis progression for osteosarcoma patients
por: Wang, Jun, et al.
Publicado: (2020)

Capu and Spire Assemble a Cytoplasmic Actin Mesh that Maintains Microtubule Organization in the Drosophila Oocyte
por: Dahlgaard, Katja, et al.
Publicado: (2007)

Histone acetyltransferase Enok regulates oocyte polarization by promoting expression of the actin nucleation factor spire
por: Huang, Fu, et al.
Publicado: (2014)

Exosomes and Exosomal circRNAs: The Rising Stars in the Progression, Diagnosis and Prognosis of Gastric Cancer
por: Lu, Ling, et al.
Publicado: (2021)

InSpire to Promote Lung Assessment in Youth: Evolving the Self-Management Paradigms of Young People With Asthma
por: Elias, Pierre, et al.
Publicado: (2013)

Spire and Formin 2 Synergize and Antagonize in Regulating Actin Assembly in Meiosis by a Ping-Pong Mechanism
por: Montaville, Pierre, et al.
Publicado: (2014)

Saving babies’ lives project impact and results evaluation (SPiRE): a mixed methodology study
por: Widdows, Kate, et al.
Publicado: (2018)

Spire1 and Myosin Vc promote Ca(2+)-evoked externalization of von Willebrand factor in endothelial cells
por: Holthenrich, Anna, et al.
Publicado: (2022)

inSPIRE: An Open-Source Tool for Increased Mass Spectrometry Identification Rates Using Prosit Spectral Prediction
por: Cormican, John A., et al.
Publicado: (2022)

circRNAs and Exosomes: A Mysterious Frontier for Human Cancer
por: Shi, Xuefei, et al.
Publicado: (2019)

Glycosyl phosphatidylinositol--anchored T-cadherin mediates calcium- dependent, homophilic cell adhesion
Publicado: (1992)

Exosomal circular RNA hsa_circ_0006220, and hsa_circ_0001666 as biomarkers in the diagnosis of pancreatic cancer
por: Hong, Lu, et al.
Publicado: (2022)

Exosome‐transmitted circ_MMP2 promotes hepatocellular carcinoma metastasis by upregulating MMP2
por: Liu, Dengrui, et al.
Publicado: (2020)

Exosomal circRNA-100338 promotes hepatocellular carcinoma metastasis via enhancing invasiveness and angiogenesis
por: Huang, Xiu-Yan, et al.
Publicado: (2020)

Circ-AKT3 inhibits clear cell renal cell carcinoma metastasis via altering miR-296-3p/E-cadherin signals
por: Xue, Dingwei, et al.
Publicado: (2019)

P-cadherin and the journey to cancer metastasis
por: Vieira, André Filipe, et al.
Publicado: (2015)

Different glycosylation of cadherins from human bladder non-malignant and cancer cell lines
por: Przybyło, Małgorzata, et al.
Publicado: (2002)

Beyond N-Cadherin, Relevance of Cadherins 5, 6 and 17 in Cancer Progression and Metastasis
por: Casal, J. Ignacio, et al.
Publicado: (2019)

DNA damage induces nuclear actin filament assembly by Formin-2 and Spire-1/2 that promotes efficient DNA repair
por: Belin, Brittany J, et al.
Publicado: (2015)

Cannot write session to /tmp/vufind_sessions/sess_poo7m8kij8k2trjab90nc5c7rk