Identification and characterization of 7-azaindole derivatives as inhibitors of the SARS-CoV-2 spike-hACE2 protein interaction

The COVID-19 pandemic, caused by SARS-CoV-2, has become a global public health crisis. The entry of SARS-CoV-2 into host cells is facilitated by the binding of its spike protein (S1-RBD) to the host receptor hACE2. Small molecule compounds targeting S1-RBD-hACE2 interaction could provide an alternat...

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Detalles Bibliográficos
Autores principales: Wang, Chaojie, He, Fengming, Sun, Ke, Guo, Kaiqiang, Lu, Sheng, Wu, Tong, Gao, Xiang, Fang, Meijuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Published by Elsevier B.V. 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10238281/
https://www.ncbi.nlm.nih.gov/pubmed/37276898
http://dx.doi.org/10.1016/j.ijbiomac.2023.125182

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10238281/
https://www.ncbi.nlm.nih.gov/pubmed/37276898
http://dx.doi.org/10.1016/j.ijbiomac.2023.125182

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