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NFYA promotes malignant behavior of triple-negative breast cancer in mice through the regulation of lipid metabolism

Two splicing variants exist in NFYA that exhibit high expression in many human tumour types. The balance in their expression correlates with prognosis in breast cancer, but functional differences remain unclear. Here, we demonstrate that NFYAv1, a long-form variant, upregulates the transcription of...

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Detalles Bibliográficos
Autores principales: Okada, Nobuhiro, Ueki, Chihiro, Shimazaki, Masahiro, Tsujimoto, Goki, Kohno, Susumu, Muranaka, Hayato, Yoshikawa, Kiyotsugu, Takahashi, Chiaki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10238388/
https://www.ncbi.nlm.nih.gov/pubmed/37268670
http://dx.doi.org/10.1038/s42003-023-04987-9