Crystal structure of LRG1 and the functional significance of LRG1 glycan for LPHN2 activation

The serum glycoprotein leucine-rich ɑ-2-glycoprotein 1 (LRG1), primarily produced by hepatocytes and neutrophils, is a multifunctional protein that modulates various signaling cascades, mainly TGFβ signaling. Serum LRG1 and neutrophil-derived LRG1 have different molecular weights due to differences...

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Detalles Bibliográficos
Autores principales: Yang, Jimin, Yin, Guo Nan, Kim, Do-Kyun, Han, Ah-reum, Lee, Dong Sun, Min, Kwang Wook, Fu, Yaoyao, Yun, Jeongwon, Suh, Jun-Kyu, Ryu, Ji-Kan, Kim, Ho Min
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10238393/
https://www.ncbi.nlm.nih.gov/pubmed/37121976
http://dx.doi.org/10.1038/s12276-023-00992-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10238393/
https://www.ncbi.nlm.nih.gov/pubmed/37121976
http://dx.doi.org/10.1038/s12276-023-00992-4

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