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An MRTF-A–ZEB1–IRF9 axis contributes to fibroblast–myofibroblast transition and renal fibrosis

Myofibroblasts, characterized by the expression of the matricellular protein periostin (Postn), mediate the profibrogenic response during tissue repair and remodeling. Previous studies have demonstrated that systemic deficiency in myocardin-related transcription factor A (MRTF-A) attenuates renal fi...

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Detalles Bibliográficos
Autores principales: Zhao, Qianwen, Shao, Tinghui, Zhu, Yuwen, Zong, Gengjie, Zhang, Junjie, Tang, Shifan, Lin, Yanshan, Ma, Hongzhen, Jiang, Zhifan, Xu, Yong, Wu, Xiaoyan, Zhang, Tao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10238398/
https://www.ncbi.nlm.nih.gov/pubmed/37121967
http://dx.doi.org/10.1038/s12276-023-00990-6