Steady-state memory-phenotype conventional CD4(+) T cells exacerbate autoimmune neuroinflammation in a bystander manner via the Bhlhe40/GM-CSF axis

Memory-phenotype (MP) CD4(+) T cells are a substantial population of conventional T cells that exist in steady-state mice, yet their immunological roles in autoimmune disease remain unclear. In this work, we unveil a unique phenotype of MP CD4(+) T cells determined by analyzing single-cell transcrip...

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Detalles Bibliográficos
Autores principales: Cho, Min-Ji, Lee, Hong-Gyun, Yoon, Jae-Won, Kim, Gil-Ran, Koo, Ja-Hyun, Taneja, Reshma, Edelson, Brian T., Lee, You Jeong, Choi, Je-Min
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10238403/
https://www.ncbi.nlm.nih.gov/pubmed/37121980
http://dx.doi.org/10.1038/s12276-023-00995-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10238403/
https://www.ncbi.nlm.nih.gov/pubmed/37121980
http://dx.doi.org/10.1038/s12276-023-00995-1

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