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Lipid droplets are a metabolic vulnerability in melanoma

Melanoma exhibits numerous transcriptional cell states including neural crest-like cells as well as pigmented melanocytic cells. How these different cell states relate to distinct tumorigenic phenotypes remains unclear. Here, we use a zebrafish melanoma model to identify a transcriptional program li...

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Detalles Bibliográficos
Autores principales: Lumaquin-Yin, Dianne, Montal, Emily, Johns, Eleanor, Baggiolini, Arianna, Huang, Ting-Hsiang, Ma, Yilun, LaPlante, Charlotte, Suresh, Shruthy, Studer, Lorenz, White, Richard M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10238408/
https://www.ncbi.nlm.nih.gov/pubmed/37268606
http://dx.doi.org/10.1038/s41467-023-38831-9