Altered Signaling and Desensitization Responses in PTH1R Mutants Associated with Eiken Syndrome

The parathyroid hormone receptor type 1 (PTH1R) is a G protein-coupled receptor that plays key roles in regulating calcium homeostasis and skeletal development via binding the ligands, PTH and PTH-related protein (PTHrP), respectively. Eiken syndrome is a rare disease of delayed bone mineralization...

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Detalles Bibliográficos
Autores principales: Portales-Castillo, Ignacio, Dean, Thomas, Cheloha, Ross W., Creemer, Brendan A., Vilardaga, Jean-Pierre, Savransky, Sofya, Khatri, Ashok, Jüppner, Harald, Gardella, Thomas J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10238420/
https://www.ncbi.nlm.nih.gov/pubmed/37268817
http://dx.doi.org/10.1038/s42003-023-04966-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10238420/
https://www.ncbi.nlm.nih.gov/pubmed/37268817
http://dx.doi.org/10.1038/s42003-023-04966-0

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