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A method for parallel microscale protein labeling and precise control over the average degree of labeling (aDoL)
A widely used approach for protein conjugation is through the lysine residues reacting with NHS- or other active esters. However, it is a challenge to precisely control the degree of labeling (DoL) due to the instability of active ester and variability of reaction efficiencies. Here, we provide a pr...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10238424/ https://www.ncbi.nlm.nih.gov/pubmed/37268718 http://dx.doi.org/10.1038/s41598-023-36163-8 |