Elevated GRO-α and IL-18 in serum and brain implicate the NLRP3 inflammasome in frontotemporal dementia

Neuroinflammation is a hallmark of frontotemporal dementia (FTD), a heterogeneous group of proteinopathies characterized by the progressive degeneration of the frontal and temporal lobes. It is marked by microglial activation and subsequent cytokine release. Although cytokine levels in FTD brain and...

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Detalles Bibliográficos
Autores principales: Lok, Hiu Chuen, Katzeff, Jared S., Hodges, John R., Piguet, Olivier, Fu, YuHong, Halliday, Glenda M., Kim, Woojin Scott
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10238432/
https://www.ncbi.nlm.nih.gov/pubmed/37268663
http://dx.doi.org/10.1038/s41598-023-35945-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10238432/
https://www.ncbi.nlm.nih.gov/pubmed/37268663
http://dx.doi.org/10.1038/s41598-023-35945-4

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