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Candesartan, an angiotensin-II receptor blocker, ameliorates insulin resistance and hepatosteatosis by reducing intracellular calcium overload and lipid accumulation

Insulin resistance is a major contributor to the pathogenesis of several human diseases, including type 2 diabetes, hypertension, and hyperlipidemia. Notably, insulin resistance and hypertension share common abnormalities, including increased oxidative stress, inflammation, and organelle dysfunction...

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Detalles Bibliográficos
Autores principales: Lee, Jin Wook, Gu, Hyun-Oh, Jung, Yunshin, Jung, YunJae, Seo, Seung-Yong, Hong, Jeong-Hee, Hong, In-Sun, Lee, Dae Ho, Kim, Ok-Hee, Oh, Byung-Chul
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10238434/
https://www.ncbi.nlm.nih.gov/pubmed/37121975
http://dx.doi.org/10.1038/s12276-023-00982-6