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Targeting the post-synaptic proteome has therapeutic potential for psychosis in Alzheimer Disease

Individuals with Alzheimer Disease who develop psychotic symptoms (AD + P) experience more rapid cognitive decline and have reduced indices of synaptic integrity relative to those without psychosis (AD-P). We sought to determine whether the postsynaptic density (PSD) proteome is altered in AD + P re...

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Detalles Bibliográficos
Autores principales: Krivinko, J. M., DeChellis-Marks, M. R., Zeng, L., Fan, P., Lopez, O. L., Ding, Y., Wang, L., Kofler, J., MacDonald, M. L., Sweet, R. A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10238472/
https://www.ncbi.nlm.nih.gov/pubmed/37268664
http://dx.doi.org/10.1038/s42003-023-04961-5