CD200R signaling contributes to unfavorable tumor microenvironment through regulating production of chemokines by tumor-associated myeloid cells

CD200 is overexpressed in many solid tumors and considered as an immune checkpoint molecule dampening cancer immunity. In this study, we found that CD200R(−/−) mice were significantly more potent in rejecting these CD200(+) tumors. scRNA sequencing demonstrated that tumors from CD200R(−/−) mice had...

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Detalles Bibliográficos
Autores principales: Lin, Cho-Hao, Talebian, Fatemeh, Li, Yang, Zhu, Jianmin, Liu, Jin-Qing, Zhao, Bolin, Basu, Sujit, Pan, Xueliang, Chen, Xi, Yan, Pearlly, Carson, William E., Xin, Gang, Wen, Haitao, Wang, Ruoning, Li, Zihai, Ma, Qin, Bai, Xue-Feng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10239067/
https://www.ncbi.nlm.nih.gov/pubmed/37275530
http://dx.doi.org/10.1016/j.isci.2023.106904

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10239067/
https://www.ncbi.nlm.nih.gov/pubmed/37275530
http://dx.doi.org/10.1016/j.isci.2023.106904

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