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Dental pulp stem cell-derived exosomes revitalize salivary gland epithelial cell function in NOD mice via the GPER-mediated cAMP/PKA/CREB signaling pathway

BACKGROUND: Restoration of salivary gland function in Sjogren’s syndrome (SS) is still a challenge. Dental pulp stem cells (DPSCs) derived exosomes had shown anti-inflammatory, anti-oxidative, immunomodulatory, and tissue function restorative abilities. However, the salivary gland function restorati...

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Detalles Bibliográficos
Autores principales: Hu, Shilin, Chen, Bo, Zhou, Jiannan, Liu, Fangqi, Mao, Tianjiao, Pathak, Janak L., Watanabe, Nobumoto, Li, Jiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10239098/
https://www.ncbi.nlm.nih.gov/pubmed/37268950
http://dx.doi.org/10.1186/s12967-023-04198-0