Clinical isolates of uncomplicated falciparum malaria from high and low malaria transmission areas show distinct pfcrt and pfmdr1 polymorphisms in western Ethiopia

BACKGROUND: Pfcrt gene has been associated with chloroquine resistance and the pfmdr1 gene can alter malaria parasite susceptibility to lumefantrine, mefloquine, and chloroquine. In the absence of chloroquine (CQ) and extensive use of artemether–lumefantrine (AL) from 2004 to 2020 to treat uncomplic...

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Detalles Bibliográficos
Autores principales: Tadele, Geletta, Jawara, Aminata, Oboh, Mary, Oriero, Eniyou, Dugassa, Sisay, Amambua-Ngwa, Alfred, Golassa, Lemu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10239113/
https://www.ncbi.nlm.nih.gov/pubmed/37270589
http://dx.doi.org/10.1186/s12936-023-04602-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10239113/
https://www.ncbi.nlm.nih.gov/pubmed/37270589
http://dx.doi.org/10.1186/s12936-023-04602-6

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