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iPSCs ameliorate hypoxia-induced autophagy and atrophy in C2C12 myotubes via the AMPK/ULK1 pathway

BACKGROUND: Duchenne muscular dystrophy (DMD) is an X-linked lethal genetic disorder for which there is no effective treatment. Previous studies have shown that stem cell transplantation into mdx mice can promote muscle regeneration and improve muscle function, however, the specific molecular mechan...

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Detalles Bibliográficos
Autores principales: Cen, Haimei, Fan, Pin, Ding, Yuting, Luo, Bin, Luo, Hong, Chen, Menglong, Zhang, Yu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10239182/
https://www.ncbi.nlm.nih.gov/pubmed/37270528
http://dx.doi.org/10.1186/s40659-023-00435-4