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Regression modelling of conditional morphogene expression links and quantifies the impact of growth rate, fitness and macromorphology with protein secretion in Aspergillus niger

BACKGROUND: Filamentous fungi are used as industrial cell factories to produce a diverse portfolio of proteins, organic acids, and secondary metabolites in submerged fermentation. Generating optimized strains for maximum product titres relies on a complex interplay of molecular, cellular, morphologi...

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Detalles Bibliográficos
Autores principales: Cairns, Timothy C., de Kanter, Tom, Zheng, Xiaomei Z., Zheng, Ping, Sun, Jibin, Meyer, Vera
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10239186/
https://www.ncbi.nlm.nih.gov/pubmed/37268954
http://dx.doi.org/10.1186/s13068-023-02345-9