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1,25-Dihydroxy Vitamin D(3) Facilitates the M2 Polarization and β-Amyloid Uptake by Human Microglia in a TREM2-Dependent Manner

Alzheimer's disease (AD) is a neurodegenerative disorder characterized by dementia as the primary clinical symptom. The production and accumulation of aggregated β-amyloid (Aβ) in patient brain tissues is one of the hallmarks of AD pathogenesis. Microglia, brain-resident macrophages, produce in...

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Detalles Bibliográficos
Autores principales: Thu, Vo Thuy Anh, Hoang, Thi Xoan, Kim, Jae Young
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10239306/
https://www.ncbi.nlm.nih.gov/pubmed/37274074
http://dx.doi.org/10.1155/2023/3483411